Ontology highlight
ABSTRACT:
SUBMITTER: Fakhouri F
PROVIDER: S-EPMC9171628 | biostudies-literature | 2022 Jun
REPOSITORIES: biostudies-literature
Fakhouri Fadi F Schwotzer Nora N Golshayan Déla D Frémeaux-Bacchi Véronique V
Kidney international reports 20220304 6
The development of complement inhibitors represented one of the major breakthroughs in clinical nephrology in the last decade. Complement inhibition has dramatically transformed the outcome of one of the most severe kidney diseases, the atypical hemolytic uremic syndrome (aHUS), a prototypic complement-mediated disorder. The availability of complement inhibitors has also opened new promising perspectives for the management of several other kidney diseases in which complement activation is involv ...[more]