An approach for evaluating the effects of dietary fiber polysaccharides on the human gut microbiome and plasma proteome.

ABSTRACT: Increases in snack consumption associated with Westernized lifestyles provide an opportunity to introduce nutritious foods into poor diets. We describe two 10-wk-long open label, single group assignment human studies that measured the effects of two snack prototypes containing fiber preparations from two sustainable and scalable sources; the byproducts remaining after isolation of protein from the endosperm of peas and the vesicular pulp remaining after processing oranges for the manufacture of juices. The normal diets of study participants were supplemented with either a pea- or orange fiber-containing snack. We focused our analysis on quantifying the abundances of genes encoding carbohydrate-active enzymes (CAZymes) (glycoside hydrolases and polysaccharide lyases) in the fecal microbiome

SUBMITTER: Delannoy-Bruno O 

PROVIDER: S-EPMC9171781 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature