Clinicopathological characteristics of pancreatic acinar cell metaplasia associated with Helicobacter pylori infection.

ABSTRACT:

Background

Pancreatic acinar cell metaplasia (PACM) has been rarely reported in the gastric mucosa. In the present study, we aimed to elucidate the clinical and pathological characteristics of PACM associated with Helicobacter pylori (H. pylori).

Method

5930 patients who underwent five- or two-point gastric biopsy according to the updated Sydney system (USS) by upper gastrointestinal endoscopy were enrolled. The patients were categorized into current H. pylori infection (CHI), post-H. pylori eradication (PHE), and non-H. pylori infection (NHI) groups according to the H. pylori infection status, and the frequency and location of PACM were compared. Additionally, a case-control study was performed to compare the USS scores between patients with CHI and PACM and those with CHI

SUBMITTER: Fuchino T 

PROVIDER: S-EPMC9171985 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature