Temporally and functionally distinct large-scale brain network dynamics supporting task switching.

ABSTRACT:

Objective

Our daily activities require frequent switches among competing responses at the millisecond time scale. We determined the spatiotemporal characteristics and functional significance of rapid, large-scale brain network dynamics during task switching.

Methods

This cross-sectional study investigated patients with drug-resistant focal epilepsy who played a Lumosity cognitive flexibility training game during intracranial electroencephalography (iEEG) recording. According to a given task rule, unpredictably switching across trials, participants had to swipe the screen in the direction the stimulus was pointing or moving. Using this data, we described the spatiotemporal characteristics of iEEG high-gamma augmentation occurring more intensely during switch than repeat trial

SUBMITTER: Mitsuhashi T 

PROVIDER: S-EPMC9173207 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature