Estimates of Japanese Encephalitis mortality and morbidity: A systematic review and modeling analysis.

ABSTRACT:

Background

Japanese Encephalitis (JE) is known for its high case fatality ratio (CFR) and long-term neurological sequelae. Over the years, efforts in JE treatment and control might change the JE fatality risk. However, previous estimates were from 10 years ago, using data from cases in the 10 years before this. Estimating JE disease severity is challenging because data come from countries with different JE surveillance systems, diagnostic methods, and study designs. Without precise and timely JE disease severity estimates, there is continued uncertainty about the JE disease burden and the effect of JE vaccination.

Methodology

We performed a systematic review to collate age-stratified JE fatality and morbidity data. We used a stepwise model selection with BIC as the selection

SUBMITTER: Cheng Y 

PROVIDER: S-EPMC9173604 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature