Not Only Systemin: Prosystemin Harbors Other Active Regions Able to Protect Tomato Plants.

ABSTRACT: Prosystemin is a 200-amino acid precursor expressed in Solanaceae plants which releases at the C-terminal part a peptidic hormone called Systemin in response to wounding and herbivore attack. We recently showed that Prosystemin is not only a mere scaffold of Systemin but, even when deprived of Systemin, is biologically active. These results, combined with recent discoveries that Prosystemin is an intrinsically disordered protein containing disordered regions within its sequence, prompted us to investigate the N-terminal portions of the precursor, which contribute to the greatest disorder within the sequence. To this aim, PS1-70 and PS1-120 were designed, produced, and structurally and functionally characterized. Both the fragments, which maintained their intrinsic disorder, were able to in

SUBMITTER: Molisso D 

PROVIDER: S-EPMC9173717 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature