Occurrence revisited: Mycobacterium avium and Mycobacterium intracellulare in potable water in the USA.

ABSTRACT: Nontuberculous mycobacterium (NTM) infections are increasing in the USA and have a high cost burden associated with treatment. Thus, it is necessary to understand what changes could be contributing to this increase in NTM disease rate. Water samples from 40 sites were collected from around the USA. They represented three water types: groundwater disinfected with chlorine and surface water disinfected with chlorine or monochloramine. Two methods, culture and qPCR, were used to measure M. avium and M. intracellulare. Heterotrophic bacteria and NTM counts were also measured. M. avium and M. intracellulare were molecularly detected in 25% (73/292) and 35% (102/292) of samples. The mean concentrations of M. avium and M. intracellulare were 2.8 × 10³ and 4.0 × 10³ genomic u

SUBMITTER: Pfaller S 

PROVIDER: S-EPMC9173748 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature