Monitoring the COVID-19 immune landscape in Japan.

ABSTRACT:

Objectives

COVID-19 vaccination in Japan started on February 17, 2021. Because the timing of vaccination and the risk of severe COVID-19 greatly varied with age, the present study aimed to monitor the age-specific fractions of the population who were immune to SARS-CoV-2 infection after vaccination.

Methods

Natural infection remained extremely rare, accounting for less than 5% of the population by the end of 2021; thus, we ignored natural infection-induced immunity and focused on vaccine-induced immunity. We estimated the fraction of the population immune to infection by age group using vaccination registry data from February 17, 2021, to October 17, 2021. We accounted for two important sources of delay: (i) reporting delay and (ii) time from vaccination until immune protect

SUBMITTER: Sasanami M 

PROVIDER: S-EPMC9173820 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature