Clinical features and prognosis of acute lymphoblastic leukemia in children with Epstein-Barr virus infection.

ABSTRACT:

Background

Acute lymphoblastic leukemia (ALL) is one of the most common malignant diseases of the hematopoietic system in children. Although the etiology of ALL is unknown, it has been reported that it may be associated with Epstein-Barr virus (EBV) infection. The aim of this study was to analyze the impact of EBV infection on the clinical features and prognosis of childhood ALL.

Methods

A total of 162 children with ALL admitted to Heilongjiang Provincial Hospital from January 2018 to December 2020 were selected for this stud, and were divided into 2 groups, infected group and non-infected group, according to whether they had EBV infection. Differences in clinical characteristics between the 2 groups were analyzed by χ² or t-test. The impact of EBV infectio

SUBMITTER: Deng W 

PROVIDER: S-EPMC9173871 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature