Lower airway microbiome of children with recurrent wheezing: a clinical cohort study.

ABSTRACT:

Background

Wheezing is one of the most common respiratory symptoms in childhood especially in infants. In recent years, the incidence of recurrent wheezing is on the rise worldwide. To investigate the lower airway microbiota in patients with recurrent wheezing and provide insights into clinical diagnosis and treatment.

Methods

This study initially enrolled 45 hospitalised children with recurrent wheezing symptoms awaiting complete fiberoptic bronchoscopy. Of these, 13 children with tracheobronchomalacia were excluded. The final population included 32 participants (group A). The control group comprised 23 children who inhaled a foreign body and were admitted to the hospital for fiberoptic bronchoscopy within 24 hours (group B). Deoxyribonucleic acid (DNA) was extracted

SUBMITTER: Zhang L 

PROVIDER: S-EPMC9173878 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature