Metagenomic profiles of the early life microbiome of Indonesian inpatient neonates and their influence on clinical characteristics.

ABSTRACT: Determining the initial normal neonatal gut microbiome is challenging. The debate regarding the sterile fetal environment is still ongoing. Therefore, studying and comparing normal and dysbiotic microbiomes requires the elucidation of both the fetal and infant microbiomes. Factors influencing the normal microbiome also include regional and genetic factors specific to different countries. Determining the normal microbiome population in our center and their association with the clinical conditions of infants is helpful as a tool for both the prevention and treatment of related diseases during neonatal care. Here, we employed metagenomic sequencing to characterize meconium and the subsequent early-life gut microbiome of preterm neonates in Jakarta, Indonesia. Microbiome diversity and complexi

SUBMITTER: Amandito R 

PROVIDER: S-EPMC9174262 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature