A systematic review and meta-analysis of the impact of the left atrial appendage closure on left atrial function.

ABSTRACT:

Background

Left atrial (LA) appendage closure (LAAC) is effective in patients with atrial fibrillation who are not candidates for long-term anticoagulation. However, the impact of LAAC on LA function is unknown. The aim of this study is to evaluate the impact of LAAC on atrial function.

Methods

This meta-analysis was conducted according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. A search strategy was designed to utilize PubMed/Medline, EMBASE, and Google scholar for studies showing the effect of LAAC on the LA function from inception to November 20, 2021. The standardized mean difference (SMD) was calculated from the means and standard deviations.

Results

Of 247 studies initially identified, 8 studies comprising 260 patients were

SUBMITTER: Mostafa MR 

PROVIDER: S-EPMC9175246 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature