Identifying large-scale recombination and capsular switching events in <i>Streptococcus agalactiae</i> strains causing disease in adults in the UK between 2014 and 2015.

ABSTRACT: Cases of invasive group B streptococcal infection in the adult UK population have steadily increased over recent years, with the most common serotypes being V, III and Ia, but less is known of the genetic background of these strains. We have carried out in-depth analysis of the whole-genome sequences of 193 clinically important group B Streptococcus (GBS) isolates (184 were from invasive infection, 8 were from non-invasive infection and 1 had no information on isolation site) isolated from adults and submitted to the National Reference Laboratory at the UK Health Security Agency between January 2014 and December 2015. We have determined that capsular serotypes III (26.9%), Ia (26.4%) and V (15.0%) were most commonly identified, with slight differences in gender and age distribution.

SUBMITTER: Khan UB 

PROVIDER: S-EPMC9176283 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature