Camel milk protein hydrosylate alleviates hepatic steatosis and hypertension in high fructose-fed rats.

ABSTRACT:

Context

Camel milk is used in traditional medicine to treat diabetes mellitus hypertension and other metabolic disorders.

Objective

This study evaluated the antisteatotic and antihypertensive effects of camel milk protein hydrolysate (CMH) in high fructose (HF)-fed rats and compared it with the effects afforded by the intact camel milk protein extract (ICM).

Materials and methods

Adult male Wistar rats were divided into 6 groups (n = 8 each) as 1) control, 2) ICM (1000 mg/kg), 3) CMH (1000 mg/kg), 4) HF (15% in drinking water), 5) HF (15%) + ICM (1000 mg/kg), and 6) HF (15%) + CMH (1000 mg/kg). All treatments were given orally for 21 weeks, daily.

Results

Both ICM and CMH reduced fasting glucose and insulin levels, serum and hepatic levels of cholesterol

SUBMITTER: Alshuniaber MA 

PROVIDER: S-EPMC9176680 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature