Lead-OR: A multimodal platform for deep brain stimulation surgery.

ABSTRACT:

Background

Deep brain stimulation (DBS) electrode implant trajectories are stereotactically defined using preoperative neuroimaging. To validate the correct trajectory, microelectrode recordings (MERs) or local field potential recordings can be used to extend neuroanatomical information (defined by MRI) with neurophysiological activity patterns recorded from micro- and macroelectrodes probing the surgical target site. Currently, these two sources of information (imaging vs. electrophysiology) are analyzed separately, while means to fuse both data streams have not been introduced.

Methods

Here, we present a tool that integrates resources from stereotactic planning, neuroimaging, MER, and high-resolution atlas data to create a real-time visualization of the implant trajectory.

SUBMITTER: Oxenford S 

PROVIDER: S-EPMC9177150 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature