Cancer-related inflammation and depressive symptoms: Systematic review and meta-analysis.

ABSTRACT:

Background

Depressive symptoms in patients with cancer are associated with poor quality of life and decreased survival. Although inflammation is reliably associated with depression in otherwise healthy individuals, the association in patients with cancer remains unclear. Given the high prevalence of cancer-related inflammation, the authors aimed to establish the relationship between inflammation and depression in cancer patients based on extant literature.

Methods

A systematic review and meta-analysis was performed using Preferred Reporting Items for Systematic Reviews and Meta-Analyses 2020 guidelines and registered under Prospero ID CRD42021226743. Three databases were searched including PubMed, the Cochrane Library, and PsycINFO using the following criteria for inclusion:

SUBMITTER: McFarland DC 

PROVIDER: S-EPMC9177733 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature