Dietary Vitamin E Intake Is Associated With a Reduced Risk of Developing Digestive Diseases and Nonalcoholic Fatty Liver Disease.
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ABSTRACT: Introduction
Vitamin E supplementation is recommended for the treatment of nonalcoholic fatty liver disease (NAFLD) for nondiabetic patients, but its preventative effects are unclear.Methods
We assessed dietary vitamin E intake with disease phenotypes and evaluated vitamin E levels with the development of NAFLD.Results
Data from >210,000 participants demonstrate that increased dietary vitamin E associates with reduced rates of several gastrointestinal diseases and reduced overall mortality. Diabetic and overweight subjects with increased vitamin E intake have fewer NAFLD diagnoses.Discussion
Our findings reveal the relevance of vitamin E consumption for several gastrointestinal diseases and warrant further mechanistic and therapeutic investigations.
SUBMITTER: Scorletti E
PROVIDER: S-EPMC9177739 | biostudies-literature | 2022 Jun
REPOSITORIES: biostudies-literature
Publications
Dietary Vitamin E Intake Is Associated With a Reduced Risk of Developing Digestive Diseases and Nonalcoholic Fatty Liver Disease.
Scorletti Eleonora E Creasy Kate Townsend KT Vujkovic Marijana M Vell Mara M Zandvakili Inuk I Rader Daniel J DJ Schneider Kai Markus KM Schneider Carolin V CV
The American journal of gastroenterology 20220314 6
<h4>Introduction</h4>Vitamin E supplementation is recommended for the treatment of nonalcoholic fatty liver disease (NAFLD) for nondiabetic patients, but its preventative effects are unclear.<h4>Methods</h4>We assessed dietary vitamin E intake with disease phenotypes and evaluated vitamin E levels with the development of NAFLD.<h4>Results</h4>Data from >210,000 participants demonstrate that increased dietary vitamin E associates with reduced rates of several gastrointestinal diseases and reduced ...[more]
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