Multifunctional green synthesized Cu-Al layered double hydroxide (LDH) nanoparticles: anti-cancer and antibacterial activities.

ABSTRACT: Doxorubicin (DOX) is a potent anti-cancer agent and there have been attempts in developing nanostructures for its delivery to tumor cells. The nanoparticles promote cytotoxicity of DOX against tumor cells and in turn, they reduce adverse impacts on normal cells. The safety profile of nanostructures is an important topic and recently, the green synthesis of nanoparticles has obtained much attention for the preparation of biocompatible carriers. In the present study, we prepared layered double hydroxide (LDH) nanostructures for doxorubicin (DOX) delivery. The Cu-Al LDH nanoparticles were synthesized by combining Cu(NO₃)₂·3H₂O and Al(NO₃)₃·9H₂O, and then, autoclave at 110. The green modification of LDH nanoparticles with Planta

SUBMITTER: Kiani M 

PROVIDER: S-EPMC9177833 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature