Circulating Extracellular Vesicles Are Strongly Associated With Cardiovascular Risk Markers.

ABSTRACT:

Background

Extracellular vesicles (EVs) are submicron membrane-bound vesicles released from various cells, which are emerging as a potential novel biomarker in cardiovascular diseases (CVDs) due to their procoagulatory and prothrombotic properties. However, there is little information about the relationships between circulating EVs and conventional and thrombogenic risk markers of CVDs.

Objective

To investigate the relationships between circulating EVs, conventional cardiovascular risk markers and thrombogenic markers in subjects with moderate risk of CVDs.

Design

Subjects (n = 40) aged 40-70 years with moderate risk of CVDs were recruited and assessed for body mass index, blood pressure and plasma lipid profile, as well as platelet aggregation, clot formation,

SUBMITTER: Zhou R 

PROVIDER: S-EPMC9178174 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature