Local Adaptation and the Evolution of Genome Architecture in Threespine Stickleback.

ABSTRACT: Theory predicts that local adaptation should favor the evolution of a concentrated genetic architecture, where the alleles driving adaptive divergence are tightly clustered on chromosomes. Adaptation to marine versus freshwater environments in threespine stickleback has resulted in an architecture that seems consistent with this prediction: divergence among populations is mainly driven by a few genomic regions harboring multiple quantitative trait loci for environmentally adapted traits, as well as candidate genes with well-established phenotypic effects. One theory for the evolution of these "genomic islands" is that rearrangements remodel the genome to bring causal loci into tight proximity, but this has not been studied explicitly. We tested this theory using synteny analysis to identif

SUBMITTER: Li Q 

PROVIDER: S-EPMC9178229 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature