Malnutrition outweighs the effect of the obesity paradox.

ABSTRACT:

Background

High body mass index (BMI) is paradoxically associated with better outcome in patients with heart failure (HF). The effects of malnutrition on this phenomenon across the whole spectrum of HF have not yet been studied.

Methods

In this observational study, patients were classified by guideline diagnostic criteria to one of three heart failure subtypes: reduced (HFrEF), mildy reduced (HFmrEF), and preserved ejection fraction (HFpEF). Data were retrieved from the Viennese-community healthcare provider network between 2010 and 2020. The relationship between BMI, nutritional status reflected by the prognostic nutritional index (PNI), and survival was assessed. Patients were classified by the presence (PNI < 45) or absence (PNI ≥ 45) of malnutrition.

Results

Of th

SUBMITTER: Prausmuller S 

PROVIDER: S-EPMC9178364 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature