Single-dose versus multiple-dose antibiotics prophylaxis for preventing caesarean section postpartum infections: A randomized controlled trial.

ABSTRACT:

Background

Caesarean section, a common obstetric surgical procedure, is a major predisposing factor for puerperal infections, requiring the need for antibiotic prophylaxis. Evidence suggests that single-dose antibiotic prophylaxis has comparable efficacy to multiple-dose antibiotic prophylaxis, but with a lower cost and risk of antibiotic resistance. However, single-dose antibiotic prophylaxis after caesarean section is not generally used in many centres in sub-Saharan Africa.

Objective

This study aimed to compare the effectiveness of single- versus multiple-dose antibiotic prophylaxis to prevent post-caesarean section infections.

Methodology

This open-label, randomized controlled trial involved 162 consenting patients admitted for caesarean section (elective or emerg

SUBMITTER: Igwemadu GT 

PROVIDER: S-EPMC9178729 | biostudies-literature | 2022 Jan-Dec

REPOSITORIES: biostudies-literature