Transcriptional and post-transcriptional regulation of young genes in plants.

ABSTRACT:

Background

New genes continuously emerge from non-coding DNA or by diverging from existing genes, but most of them are rapidly lost and only a few become fixed within the population. We hypothesized that young genes are subject to transcriptional and post-transcriptional regulation to limit their expression and minimize their exposure to purifying selection.

Results

We performed a protein-based homology search across the tree of life to determine the evolutionary age of protein-coding genes present in the rice genome. We found that young genes in rice have relatively low expression levels, which can be attributed to distal enhancers, and closed chromatin conformation at their transcription start sites (TSS). The chromatin in TSS regions can be re-modeled in response to abiot

SUBMITTER: Raxwal VK 

PROVIDER: S-EPMC9178820 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature