Extramedullary hematopoiesis in an inguinal lymph node: an unusual presentation of primary myelofibrosis.

ABSTRACT:

Background

Extramedullary hematopoiesis (EMH) is a proliferation of hematopoietic tissue outside of the bone marrow medullary space. It is a pathophysiologic response, more often associated with either a benign reactive hematological disease or a myeloproliferative neoplasm (MPN). Identification of EMH in adults is always pathologic. It is highly unlikely for a myeloproliferative neoplasm to present with inguinal lymphadenopathy. An unusual and complex case can be precisely diagnosed via a multidisciplinary approach involving experts from various modalities of laboratory. In this regard, the present case highlights the importance of an integrated approach in establishing the diagnosis.

Case presentation

We report a case of a 61-year-old male patient of primary myelofibrosis

SUBMITTER: Yaqoob N 

PROVIDER: S-EPMC9178870 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature