Clinical and subclinical acute kidney injury in children with mild-to-moderate COVID-19.

ABSTRACT:

Background

Our aim was to identify acute kidney injury (AKI) and subacute kidney injury using both KDIGO criteria and urinary biomarkers in children with mild/moderate COVID-19.

Methods

This cross-sectional study included 71 children who were hospitalized with a diagnosis of COVID-19 from 3 centers in Istanbul and 75 healthy children. We used a combination of functional (serum creatinine) and damage (NGAL, KIM-1, and IL-18) markers for the definition of AKI and subclinical AKI. Clinical and laboratory features were evaluated as predictors of AKI and subclinical AKI.

Results

Patients had significantly higher levels of urinary biomarkers and urine albumin-creatinine ratio than healthy controls (p < 0.001). Twelve patients (16.9%) developed AKI based on KDIGO criteria, a

SUBMITTER: Saygili S 

PROVIDER: S-EPMC9178933 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature