Consumption of whole grains and risk of type 2 diabetes: A comprehensive systematic review and dose-response meta-analysis of prospective cohort studies.

ABSTRACT: This study aimed to quantitatively summarize earlier findings on the association between whole grain (WG) intake and type 2 diabetes (T2D) risk. We searched related keywords on PubMed/Medline, Scopus, and Google Scholar up to October 2021. Prospective observational studies investigating the association between WG intake and risk of T2D were included. The random-effects model calculates the summary relative risks by contrasting categories and linear and nonlinear dose-response associations. Eleven prospective cohort studies, including 463,282 participants and 37,249 type 2 diabetes incidents, were analyzed. The pooled relative risk (RR) for the highest versus the lowest WG intake category indicated a 21% decrease in T2D risk (95% confidence interval (CI): 0.73-0.85, I ² =

SUBMITTER: Ghanbari-Gohari F 

PROVIDER: S-EPMC9179146 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature