Recent Applications of Artificial Intelligence from Histopathologic Image-Based Prediction of Microsatellite Instability in Solid Cancers: A Systematic Review

ABSTRACT:

Simple Summary

Although the evaluation of microsatellite instability (MSI) is important for immunotherapy, it is not feasible to test MSI in all cancers due to the additional cost and time. Recently, artificial intelligence (AI)-based MSI prediction models from whole slide images (WSIs) are being developed and have shown promising results. However, these models are still at their elementary level, with limited data for validation. This study aimed to assess the current status of AI applications to WSI-based MSI prediction and to suggest a better study design. The performance of the MSI prediction models were promising, but a small dataset, lack of external validation, and lack of a multiethnic population dataset were the major limitations. Through a combination with high-sensitivi

SUBMITTER: Alam M 

PROVIDER: S-EPMC9179592 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature