Stereotactic Body Radiation Therapy (SBRT) for Oligorecurrent/Oligoprogressive Mediastinal and Hilar Lymph Node Metastasis: A Systematic Review.

ABSTRACT:

Introduction

Mediastinal or hilar lymph node metastases are a challenging condition in patients affected by solid tumors. Stereotactic body radiation therapy (SBRT) could play a crucial role in the therapeutic management and in the so-called "no-fly zone", delivering high doses of radiation in relatively few treatment fractions with excellent sparing of healthy surrounding tissues and low toxicity. The aim of this systematic review is to evaluate the feasibility and tolerability of SBRT in the treatment of mediastinal and hilar lesions with particular regard to the radiotherapy doses, dose constraints for organs at risk, and clinical outcomes.

Materials and methods

Two blinded investigators performed a critical review of the Medline, Web of Knowledge, Google Scholar, Scopus,

SUBMITTER: Cozzi S 

PROVIDER: S-EPMC9179886 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature