Treatment Adherence and Health-Related Quality of Life in Patients with Hemophilia in Hong Kong.

ABSTRACT:

Background

This study aims to identify factors affecting health-related quality of life (HRQoL) in Chinese patients with hemophilia in Hong Kong, and to examine the association between treatment adherence and HRQoL outcomes.

Methods

Patients with hemophilia A or B from a non-governmental organization reported their HRQoL and treatment adherence to prophylactic therapy using validated tools. Univariate tests and multivariable regression analysis were used to compare differences in outcomes across clinically relevant subgroups.

Results

Fifty-six patients were recruited (mean age 30.4 [17.4] years; majority hemophilia A: 75%; moderate-to-severe severity: 88%). Patients who received prophylactic treatment reported fewer work/school problems (25.8 [18.9] versus 51.5 [26.3]

SUBMITTER: Cheung YT 

PROVIDER: S-EPMC9180237 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature