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Thyroid Dysfunction and COVID-19: The Emerging Role of Selenium in This Intermingled Relationship.


ABSTRACT: COVID-19 represents a worldwide public health emergency, and, beyond the respiratory symptoms characterizing the classic viral disease, growing evidence has highlighted a possible reciprocal relationship between SARS-CoV-2 infection and thyroid dysfunction. The updated data discussed in this review suggests a role of SARS-CoV-2 infection on the thyroid gland, with multiple thyroid pictures described. Conversely, no conclusion can be drawn on the association between pre-existing thyroid disease and increased risk of SARS-CoV-2 infection. In this scenario, selenium (Se), an essential trace element critical for thyroid function and known as an effective agent against viral infections, is emerging as a potential novel therapeutic option for the treatment of COVID-19. Large multicentre cohort s

SUBMITTER: Gorini F 

PROVIDER: S-EPMC9180529 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature