Dataset Information

Association between Neck Circumference and Subclinical Atherosclerosis among Chinese Steelworkers: A Cross-Sectional Survey.

ABSTRACT: The purpose of this study was to determine whether neck circumference (NC) is associated with subclinical atherosclerosis among Chinese steelworkers in North China. A cross-sectional survey was conducted among steelworkers in northern China (n = 3467). Carotid intima-media thickness (CIMT) was measured at the distal wall of the common carotid artery proximal to the bifurcation point along a plaque-free segment 10 mm long on each side by B-ultrasound. The mean of the common CIMT was used bilaterally in this study. In the cross-sectional analysis, large NC was associated with the presence of abnormal CIMT. Logistic regression analysis was used to assess the relationship between NC tertiles and CIMT. The multivariable-adjusted odds ratio was 1.76 (95% CI: 1.40 to 2.22; p for trend <0.001) for the highest tertile versus the lowest tertile and was 1.07 (95% CI: 1.04 to 1.10; p < 0.001) per 1 standard deviation increment in NC. Among steelworkers in North China, relatively large NC level is associated with elevated odds of subclinical atherosclerosis.

SUBMITTER: Yu M

PROVIDER: S-EPMC9180598 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature

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Publications

Association between Neck Circumference and Subclinical Atherosclerosis among Chinese Steelworkers: A Cross-Sectional Survey.

Yu Miao M Wang Lihua L Zhang Shengkui S Feng Hongman H Wu Jianhui J Li Xiaoming X Yuan Juxiang J

International journal of environmental research and public health 20220531 11

The purpose of this study was to determine whether neck circumference (NC) is associated with subclinical atherosclerosis among Chinese steelworkers in North China. A cross-sectional survey was conducted among steelworkers in northern China (n = 3467). Carotid intima-media thickness (CIMT) was measured at the distal wall of the common carotid artery proximal to the bifurcation point along a plaque-free segment 10 mm long on each side by B-ultrasound. The mean of the common CIMT was used bilatera ...[more]

PMID: 35682318

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Project description:This study aims to explore the association between the triglyceride-glucose (TyG) index and the risk of carotid atherosclerosis (CAS) among Chinese steelworkers. This is a cross-sectional study involving a total of 4,203 Chinese steelworkers. The TyG index was calculated using the formula: TyG = Ln [fasting triglycerides (mg/dL) × fasting glucose (mg/dL) / 2]. The association between the TyG index and CAS was analyzed using multivariable logistic regression and restricted cubic spline (RCS) models. The association between TyG and CAS was evaluated across different subgroups, including sex, age, lifestyle, medical history, and the state of occupational exposure. In addition, the TyG index was used to perform calibration and risk reclassification analyses on the fully adjusted model. Feature importance and predictive models were generated using LASSO regression and machine learning methods. In the fully adjusted model, compared to the lowest quartile group, the odds ratios (OR, 95% CI) for CAS, increased CIMT, and plaque in the highest quartile group of the TyG index were 3.199 (2.423 ~ 4.223), 2.877 (2.149 ~ 3.851), and 3.738 (2.700 ~ 5.177), respectively. Steelworkers exposed to occupational hazards had a higher risk of CAS compared to those not exposed. There was a nonlinear positive correlation between the TyG index and CAS (P < 0.05), and the risk of CAS increased when TyG > 8.72. Additionally, the TyG index demonstrated additional predictive capability beyond existing risk factors, significantly improving discriminatory performance (P < 0.05). In LASSO regression, TyG index and other covariables are screened as important feature variables to be incorporated into the development of machine learning models. The TyG index is associated with an increased risk of CAS among steelworkers, underscoring its potential as a reliable and practical predictive tool for assessing CAS risk in this population. Steelworkers with a TyG index>8.72 should receive additional CAS screening and health interventions. In addition, attention should be paid to those exposed to occupational hazards. The TyG index may serve as a simple, rapid, and reliable assessment tool for identifying high-risk individuals with CAS among steelworkers.

Dataset Information

Association between Neck Circumference and Subclinical Atherosclerosis among Chinese Steelworkers: A Cross-Sectional Survey.

Publications

Association between Neck Circumference and Subclinical Atherosclerosis among Chinese Steelworkers: A Cross-Sectional Survey.

Similar Datasets

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