Insights into the Transcriptional Reprogramming in Tomato Response to PSTVd Variants Using Network Approaches.

ABSTRACT: Viroids are the smallest pathogens of angiosperms, consisting of non-coding RNAs that cause severe diseases in agronomic crops. Symptoms associated with viroid infection are linked to developmental alterations due to genetic regulation. To understand the global mechanisms of host viroid response, we implemented network approaches to identify master transcription regulators and their differentially expressed targets in tomato infected with mild and severe variants of PSTVd. Our approach integrates root and leaf transcriptomic data, gene regulatory network analysis, and identification of affected biological processes. Our results reveal that specific bHLH, MYB, and ERF transcription factors regulate genes involved in molecular mechanisms underlying critical signaling pathways. Functional enr

SUBMITTER: Avina-Padilla K 

PROVIDER: S-EPMC9181013 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature