Documenting the epidemiologic patterns of polyomaviruses in human populations by studying their presence in urban sewage.

ABSTRACT: This is the first description, to our knowledge, of the distribution of human polyomavirus and simian virus 40 (SV40) in urban sewage. Using a nested-PCR procedure, we report the detection of human polyomaviruses JC virus (JCV) and BK virus (BKV) but not SV40 in a high percentage of urban sewage samples obtained from widely divergent geographical areas in Europe and Africa. For a total of 28 samples analyzed, JCV was detected in 26, BKV was detected in 22, and none was positive for SV40. All geographical areas showed a high prevalence of these viruses with mean estimated values of JC viral particles per ml on the order of 10(3) in Barcelona (Spain) and Nancy (France) and 10(2) in Pretoria (South Africa) and Umeå (Sweden) and mean values of BK viral particles on the order of 10(2) in Pretor

SUBMITTER: Bofill-Mas S 

PROVIDER: S-EPMC91812 | biostudies-literature | 2000 Jan

REPOSITORIES: biostudies-literature