Characterization of the Biomass Degrading Enzyme GuxA from Acidothermus cellulolyticus.

ABSTRACT: Microbial conversion of biomass relies on a complex combination of enzyme systems promoting synergy to overcome biomass recalcitrance. Some thermophilic bacteria have been shown to exhibit particularly high levels of cellulolytic activity, making them of particular interest for biomass conversion. These bacteria use varying combinations of CAZymes that vary in complexity from a single catalytic domain to large multi-modular and multi-functional architectures to deconstruct biomass. Since the discovery of CelA from Caldicellulosiruptor bescii which was identified as one of the most active cellulase so far identified, the search for efficient multi-modular and multi-functional CAZymes has intensified. One of these candidates, GuxA (previously Acel_0615), was recently shown to exhibit synergy

SUBMITTER: Hengge NN 

PROVIDER: S-EPMC9181691 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature