Oxidative Balance Score during Pregnancy Is Associated with Oxidative Stress in the CANDLE Study.

ABSTRACT: The objective of this study was to calculate an oxidative balance score (OBS) utilizing diet and lifestyle information collected from 1322 women during the second trimester of pregnancy in the Conditions Affecting Neurocognitive Development and Learning in Early Childhood study. An energy-adjusted OBS was calculated using nutrient information from a Food Frequency Questionnaire (FFQ), lifestyle measures, and plasma folate and vitamin D levels. Using the least absolute shrinkage and selection operator method, 91 food items from the FFQ were selected and they accounted for 82% of the variance in the OBS, with cruciferous vegetables, citrus fruits, fruit juice, and coffee being among the highest anti-oxidant predictors, and red meats and alcohol among the highest pro-oxidant contributors. Uri

SUBMITTER: Tylavsky FA 

PROVIDER: S-EPMC9182929 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature