Pharmacologic and Acute Management of Spinal Cord Injury in Adults and Children.

ABSTRACT:

Purpose of review

This review provides guidance for acute spinal cord injury (SCI) management through an analytical assessment of the most recent evidence on therapies available for treating SCI, including newer therapies under investigation. We present an approach to the SCI patient starting at presentation to acute rehabilitation and prognostication, with additional emphasis on the pediatric population when evidence is available.

Recent findings

Further studies since the Surgical Timing in Acute Spinal Cord Injury Study (STASCIS) demonstrated a potential functional outcome benefit with ultra-early surgical intervention ≤ 8 h post-SCI. Subsequent analysis of the National Acute Spinal Cord Injury Study (NASCIS) II and NASCIS III trials have demonstrated potentially serious c

SUBMITTER: Thomas AX 

PROVIDER: S-EPMC9184374 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature