Chronic urticaria and thyroid autoimmunity: a meta-analysis of case-control studies.

ABSTRACT:

Purpose

Autoimmunity has been implicated in some patients with idiopathic chronic urticaria (CU). Because of the frequency of autoimmune thyroid diseases, their association with CU deserves special attention. We tested both the existence and the extent of an association between thyroid autoimmunity and CU.

Methods

A thorough search of PubMed, Scopus, Web of Science, and Cochrane databases was performed. Studies reporting the positivity rate for anti-thyroperoxidase antibodies (TPOAbs) in people with (cases) and without CU (controls) were included. Quality of the studies was assessed by the Newcastle-Ottawa Scale. Between-study heterogeneity was assessed by Cochrane Q and I² tests, and the odds ratio (OR) for TPOAbs positivity was combined using random-effects mode

SUBMITTER: Tienforti D 

PROVIDER: S-EPMC9184403 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature