Elderly kidney transplant recipients have favorable outcomes but increased infection-related mortality.

ABSTRACT:

Background

The number of elderly patients with end-stage kidney disease has been increasing, but the outcomes of kidney transplants (KT) remain poorly understood in elderly patients. Therefore, we evaluated the clinical outcomes of elderly KT recipients and analyzed the impact of elderly donors.

Methods

This retrospective cohort study included patients who underwent KT between 2000 and 2019. KT recipients were divided into four groups according to a combination of recipient and donor age (≥60 or <60 years); elderly recipients: old-to-old (n = 46) and young-to-old (n = 83); young recipients: old-to-young (n = 98) and young-to-young (n = 796). We compared the risks of mortality, graft failure, and acute rejection between groups using Cox regression analysis.

Results

The

SUBMITTER: Lim JH 

PROVIDER: S-EPMC9184840 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature