Prevalence of Y chromosome microdeletions among infertile Mongolian men.

ABSTRACT:

Objective

Y chromosome microdeletions are the second most common genetic cause of male infertility after Klinefelter syndrome. The aim of this study was to determine the patterns of Y chromosome microdeletions among infertile Mongolian men.

Methods

A descriptive study was performed on 75 infertile men from February 2017 to December 2018. Y chromosome microdeletions were identified by polymerase chain reaction. Semen parameters, hormonal levels, and testis biopsy samples were examined.

Results

Among 75 infertile men, two cases of Y chromosome microdeletions were identified. The first case had an AZFa complete deletion and the other had an AZFc partial deletion. This study found that the proportion of Y chromosome microdeletions among infertile Mongolian men was 2.66%.<

SUBMITTER: Damdinsuren E 

PROVIDER: S-EPMC9184878 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature