Neurodevelopmental Outcomes at 1 Year in Infants of Mothers Who Tested Positive for SARS-CoV-2 During Pregnancy.

ABSTRACT:

Importance

Epidemiologic studies suggest maternal immune activation during pregnancy may be associated with neurodevelopmental effects in offspring.

Objective

To evaluate whether in utero exposure to SARS-CoV-2 is associated with risk for neurodevelopmental disorders in the first 12 months after birth.

Design, setting, and participants

This retrospective cohort study examined live offspring of all mothers who delivered between March and September 2020 at any of 6 Massachusetts hospitals across 2 health systems. Statistical analysis was performed from October to December 2021.

Exposures

Maternal SARS-CoV-2 infection confirmed by a polymerase chain reaction test during pregnancy.

Main outcomes and measures

Neurodevelopmental disorders determined from Inter

SUBMITTER: Edlow AG 

PROVIDER: S-EPMC9185175 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature