Longitudinal changes of white matter microstructure following traumatic brain injury in U.S. military service members.

ABSTRACT: The purpose of this study was to analyze quantitative diffusion tensor imaging measures across the spectrum of traumatic brain injury severity and evaluate their trajectories in military service members. Participants were 96 U.S. military service members and veterans who had sustained a mild traumatic brain injury [including complicated mild traumatic brain injury (n = 16) and uncomplicated mild traumatic brain injury (n = 68)], moderate-severe traumatic brain injury (n = 12), and controls (with or without orthopaedic injury, n = 39). All participants had been scanned at least twice, with some receiving up to five scans. Both whole brain voxel-wise analysis and tract-of-interest analysis were applied to assess the group differences of diffusion tensor imaging me

SUBMITTER: Yeh PH 

PROVIDER: S-EPMC9185378 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature