Efficacy of Marine ω-3 Fatty Acid Supplementation vs Placebo in Reducing Incidence of Dry Eye Disease in Healthy US Adults: A Randomized Clinical Trial.

ABSTRACT:

Importance

Results of several small randomized clinical trials have suggested that supplements of marine ω-3 fatty acids may be beneficial in treating signs and symptoms of dry eye disease (DED). However, randomized clinical trial data to examine whether ω-3 fatty acid supplements can prevent DED are lacking.

Objective

To evaluate whether long-term daily supplementation with marine ω-3 fatty acids prevents the development of DED.

Design, setting, and participants

This was a prespecified ancillary study of the Vitamin D and Omega-3 Trial (VITAL), a nationwide randomized double-blind placebo-controlled 2 × 2 factorial trial of vitamin D and marine ω-3 fatty acids in the primary prevention of cancer and cardiovascular disease. Participants in this ancillary study were 23

SUBMITTER: Christen WG 

PROVIDER: S-EPMC9185512 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature