Oral glucose tolerance testing as a complement to fasting plasma glucose in screening for type 2 diabetes: population-based cross-sectional analyses of 146 000 health examinations in Vasterbotten, Sweden.

ABSTRACT:

Objective

To assess the effect of adding an oral glucose tolerance test (OGTT) to fasting plasma glucose (FPG) in terms of detection of type 2 diabetes (T2D) and impaired glucose tolerance (IGT).

Design

Retrospective analysis of serial cross-sectional screening study.

Setting

Population-based health examinations within primary care in Västerbotten County, Sweden.

Participants

Individuals aged 40- 50 and 60 years with participation from 1985 to 2017. Those with previously diagnosed diabetes and FPG≥7 mmol/L were excluded.

Primary and secondary outcome measures

Prevalence of hyperglycaemia on the OGTT (IGT and T2D defined as 2-hour postload capillary plasma glucose of 8.9-12.1 mmol/L and ≥12.2 mmol/L, respectively). Analyses were further stratified by age,

SUBMITTER: Rosen A 

PROVIDER: S-EPMC9185658 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature