Evaluation of short-term epigenetic age fluctuation.
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ABSTRACT:
SUBMITTER: Komaki S
PROVIDER: S-EPMC9185970 | biostudies-literature | 2022 Jun
REPOSITORIES: biostudies-literature
Publications
Evaluation of short-term epigenetic age fluctuation.
Komaki Shohei S Ohmomo Hideki H Hachiya Tsuyoshi T Sutoh Yoichi Y Ono Kanako K Furukawa Ryohei R Umekage So S Otsuka-Yamasaki Yayoi Y Minabe Shiori S Takashima Akira A Tanno Kozo K Sasaki Makoto M Shimizu Atsushi A
Clinical epigenetics 20220609 1
Considerable effort has been spent on lowering and maintaining the epigenetic age. However, the extent to which epigenetic age fluctuates under normal conditions is poorly understood. Therefore, we analyzed methylation data from monocytes and peripheral blood mononuclear cells collected from two Japanese men. The ranges of the Pan-tissue, Skin and blood, and DNAm PhenoAge epigenetic age during 3 months were ≥ 5.62, ≥ 3.04, and ≥ 8.23 years, and the maximum daily changes were 5.21, 3.20, and 6.53 ...[more]
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