Optimizing the clinical management of EGFR-mutant advanced non-small cell lung cancer: a literature review.

ABSTRACT:

Background and objective

Despite several steps forward in the treatment of epidermal growth factor receptor (EGFR)-mutant non-small cell lung cancer (NSCLC), however there are still pending issues and upcoming challenges requiring adequate addressing in order to optimize the clinical management of metastatic patients harboring molecular alterations within the EGFR gene. This review aims to summarize the most recent findings regarding the diagnostic testing and therapeutic strategies of EGFR-mutant advanced NSCLC.

Methods

Literature search was conducted using MEDLINE/PubMed, EMBASE, Scopus and Cochrane Library databases, up to December 2021. Relevant studies in English language published between 2004 and 2021 were selected.

Key content and findings

SUBMITTER: Passiglia F 

PROVIDER: S-EPMC9186167 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature