Bone metastases in non-small cell lung cancer: a narrative review.

ABSTRACT:

Background and objective

Bone metastases are common in patients with non-small cell lung cancer (NSCLC) and remain a significant source of morbidity, mortality, and diminished quality of life, despite the considerable progress made in the overall management of patients with metastatic NSCLC over the last decade. Understanding the molecular pathogenesis of bone metastases is critical to improving survival, preserving function, and managing symptoms in this patient population. The objective of our review is to provide a comprehensive review of the pathophysiology, clinical presentation, management, and factors predicting the development and prognosis of patients with NSCLC with bone metastases.

Methods

An online electronic search was performed on PubMed and Google Scholar of a

SUBMITTER: Knapp BJ 

PROVIDER: S-EPMC9186248 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature