On-scalp magnetocorticography with optically pumped magnetometers: Simulated performance in resolving simultaneous sources.

ABSTRACT: Currently, the gold standard for high-resolution mapping of cortical electrophysiological activity is invasive electrocorticography (ECoG), a procedure that carries with it the risk of serious morbidity and mortality. Due to these risks, the use of ECoG is largely limited to pre-surgical mapping in intractable epilepsy. Nevertheless, many seminal studies in neuroscience have utilized ECoG to explore domains such as visual perception, attention, auditory processing, and sensorimotor behavior. Studies such as these, occurring in patients with epilepsy rather than healthy controls, may lack generalizability, and are limited by the placement of the electrode arrays over the presumed seizure focus. This manuscript explores the use of optically pumped magnetometers (OPMs) to create a non-invasiv

SUBMITTER: Nugent AC 

PROVIDER: S-EPMC9186482 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature