The Breast Cancer Weight Loss trial (Alliance A011401): A description and evidence for the lifestyle intervention.

ABSTRACT: The Breast Cancer Weight Loss (BWEL) trial is a randomized controlled trial designed to determine whether weight loss after a breast cancer diagnosis can reduce the risk of cancer recurrence in women with overweight or obesity. The BWEL trial will compare the efficacy of a telephone-based weight-loss intervention plus health education materials versus health education materials alone on invasive disease-free survival in 3,181 women with stage II or III breast cancer and BMI > 27 kg/m² . This report provides a detailed description of the goals and methods of the lifestyle intervention and the evidence supporting the intervention used in the BWEL trial. The intervention's primary goal for participants is to achieve and maintain a weight loss ≥ 10% of baseline weight through increa

SUBMITTER: Delahanty LM 

PROVIDER: S-EPMC9186690 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature