Impact of universal varicella vaccination on the use and cost of antibiotics and antivirals for varicella management in the United States.

ABSTRACT:

Background

Our objective was to estimate the impact of universal varicella vaccination (UVV) on the use and costs of antibiotics and antivirals for the management of varicella among children in the United States (US).

Methods

A decision tree model of varicella vaccination, infections and treatment decisions was developed. Results were extrapolated to the 2017 population of 73.5 million US children. Model parameters were populated from published sources. Treatment decisions were derived from a survey of health care professionals' recommendations. The base case modelled current vaccination coverage rates in the US with additional scenarios analyses conducted for 0%, 20%, and 80% coverage and did not account for herd immunity benefits.

Results

Our model estimated that 55

SUBMITTER: Pawaskar M 

PROVIDER: S-EPMC9187103 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature