Factors Associated with Late Local Radiation Toxicity after Post-Operative Breast Irradiation.

ABSTRACT:

Purpose

To assess determinants associated with late local radiation toxicity in patients treated for breast cancer.

Methods

A systematic review was performed. All studies reporting ≥2 variables associated with late local radiation toxicity after treatment with postoperative whole breast irradiation were included. Cohort studies, randomized controlled trials, and cross-sectional studies were eligible designs. Study characteristics and definitions of determinants and outcome measures were extracted. If possible, the measure of association was extracted.

Results

Twenty-one studies were included in this review. Six out of seven studies focused on the association between radiotherapy (boost) dose or irradiated breast volume and late radiation toxicity found significant res

SUBMITTER: Batenburg MCT 

PROVIDER: S-EPMC9187272 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature